Practical Lunacy has ALWAYS been interactive via a chat room.
In the beginning, there was an IRC server just for "TOTG", and Luna was not allowed to use any other chat platforms. Since the guys of "TOTG" were pretty much in charge at the time, she just had to do what they said, and this was one of their rules.
Then there was mystnet. A server that Luna and a few friends were in charge of. This gave the distinct advantage of having an irc.practicallunacy mask, which was pretty darn cool.
For a very long time, the show's chat room was just the chat room that Luna used for her personal chat, #MoonsRoom on the IRC Undernet.
These days, it's on Dalnet, and has been for some time. It works, so it'll stay that way for the foreseeable future.